A Review on The Concept of Organelle Ageing w.s.r. Rasayana

Abstract

Ayurveda is the science which deals with every aspect of life. This teaches us how to lead a healthy, happy and long life. The Aim of Ayurveda is to maintain the health of healthy and cure the diseases of diseased. Ayurveda is categorized into eight different branches and collectively it is known as Ashtanga Ayurveda.Out of the eight branches of Ayurveda, Rasayana Chikitsa is the one branch. In this, ageing is considered as disease due to natural process of degeneration and thus preventing premature ageing in a healthy way is also considered under the aspect of Rasayana. Thus, simply we can say Rasayana is a therapeutic Measure which promotes longevity, prevents ageing and provide immunity against diseases. Guduchi (Tinospora cordifolia) of family Menispermaceae is commonly called as Giloy, also known by the names of Rasayani (rejuvenating), Chakralakshna (as stem has circular wheel-like structur). Acharyacharak has included Guduchi in Vayasthapana Mahakasaya which improves the quality of dhatus and act as Rasayana .Guduchi is also known by the name of Amruta because of its divine fluidity. Description of Guduchi action and indication of it in different texts through different time frames confirm the continuous use of the drug since long time. Guduchi is described under Padamakadigana, Patoladigana, Guduchyadi Gana, Aragwadhadi Gana and Vachadi Gana. In Agryaprakrana, Acharya Charaka has described Giloy as the Dravya which work as Sangrahak, Vatahara and Deepenaya. To substantiate the above facts research was conducted on animal model Drosophila melanogaster, where the effect of Guduchi Churna was observed in enhancing the life span of it and was suggestive of Rasayana effect of Guduchi Churna. Hence, this paper attempts to explain the Rasayana effect of Guduchi Churna in the life span of human beings.

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